Legionella: macrolides or quinolones?

REVIEW Legionella: macrolides or quinolones?

Following the first outbreaks of legionnaire’s disease, erythromycin emerged as the treatment of choice without the foundation of rigorous clinical trials. The number of therapeutic failures with erythromycin, as well as the side-effects and drug interactions, led to the consideration of other drugs such as the new macrolides and quinolones for the treatment of legionnaire’s disease in the 1990...

Experimental pleurodesis induced by antibiotics (macrolides or quinolones).

PURPOSE Chemical pleurodesis is a therapeutic tool for the treatment of recurrent pleural effusions, mainly those of neoplastic etiology. In the past, tetracycline was the sclerosant agent of choice in clinical practice, but presently, there is no consensus about an ideal agent. The aim of this study was to evaluate the effectiveness of macrolides (azithromycin and clarithromycin) or quinolones...

New macrolides or new quinolones as monotherapy for patients with community-acquired pneumonia: our cup runneth over?

Microbiological Screening Method for Detection of Aminoglycosides, Β-lactames, Macrolides, Tetracyclines and Quinolones in Meat Samples

Antimicrobials are classified according to their chemical structure. Each class is characterized by a typical core structure and various members of the class are differentiated by the addition or removal of secondary chemical structures (1, 2). Antimicrobials can also be classified as broad or narrow spectrum, depending on the range of bacterial species against which they are active, or as bact...

Macrolides, quinolones and amoxicillin/clavulanate for chronic bronchitis: a meta-analysis.

The comparative effectiveness and safety of macrolides, quinolones and amoxicillin/clavulanate (A/C) for the treatment of patients with acute bacterial exacerbation of chronic bronchitis (ABECB) was evaluated in the present study. PubMed, Current Contents and the Cochrane Central Register of Controlled Trials were searched to identify relevant randomised controlled trials (RCTs). In total, 19 R...